Pseudoexfoliation glaucoma (PEG) is a common cause of blindness worldwide and tends to be more progressive and serious compared to primary OAG (POAG).

Overall, 50% of patients with PXF are ultimately diagnosed with glaucoma. Therefore annual assessment is required. Patients who do develop PXF glaucoma are thought to have a worse prognosis than patients with POAG, with faster rates of progression, poorer response to medications and an increased need for surgery.

Risk Factors Another major risk factor is age, as pseudoexfoliation syndrome rarely occurs in individuals under the age of 50. Other risk factors associated with this disorder include living at higher altitudes or in northern latitudes, and disproportionately high exposure to ultraviolet light.

This syndrome refers to a condition that involves the entire body but manifests primarily in the eyes. Pseudoexfoliation glaucoma, or pseudoexfoliative glaucoma, is the same condition with the addition of elevated eye pressure and evidence of damage to the optic nerve.